So, what happens now, does my Osteoporosis get progressively worse over time? I was prescribed Alendronic Acid 70 mg by my GP a couple of months go due to fracturing my humorous after I tripped me fell. Dentist now tells me my teeth are not strong enough to hold a bridge again. The side effect possibilities worry me. I am on prednisolone for polymyalgia. Took AA on Sunday and the next night I was in so much pain, I couldnt move. Dont freeze it but keep it at room temperature between 15-30C. I had vivid dreams, some headaches and didnt sleep well to start with. I can't even eat an orange on an empty stomach as it hurts so much. Like a lot of people I was researching AA70 when I came across this group. Took 1 pill of AA. Had this procedure yesterday 30th Jan 2021 (My Birthday ) Found absolutely nothing clean bill of health with my colon Such a relief Guess I will never know for sure if the medication was responsible but I am convinced that it was & will never ever take AA + ADCAL3D again. Dr David Brownstein has written, and talked on YouTube on this subject. I just took my 8th dose of alendronate sodium 70 mg. Following breast cancer they want me to take Aromatase Inhibitor along with a Biphosphonate Clondronate or Zolendronic so my question to everyone out there will these other biphosphonates result in similar pain? If you missed a dose, take it the following day and do not double take it to avoid overdosing. Until recently I only took my Thyroid med. Im 59 and have a very physical job which involves a lot of walking, and I was told by a clinician when I first started treatment that it cant help the spine anyway! It starts after some seemingly minor jaw trauma, but jaw osteonecrosis can quickly decimate a jawbone. My older sister, who had recently discovered she had osteoporosis, had a very bad fall, ironically as a result of a violent reaction to a prescription drug, and broke three vertebrae in her back. However for the past couple of months the left lower side of my face has been continuously swollen and my family have finally noticed. Im just another person looking for help with my bones, having been told by my doctor that there is no alternative to Alendronic Acid. Hello Barbara Also take two drugs for cholesterol and statins i rattle !! Again i had another Dexa scan 2 years ago and it was found i have oesteoporosis in the spine which i feel very worried about it. I have also been taking Adcal tablets for years. My mom who is 76 has taken 7 tablets, she stopped due to pain in her hips legs and groin. Your dosing may depend on your age, how severe your bone condition is, other medical conditions you have, and your reaction to the first dose. What is Alendronic acid 70mg tablets used for? cant belive my GP gave me these awful tablets . I walked home very gingerly with the dog and later phoned my doctor 4 days after my 6th dose, I woke up in the night with right hip pain. I began to take as prescribed and do not have any problems until 6 days after my 4 th dose, I was awakened in the night with uncomfortable, aching wrists. And of course I couldnt exercise, so taking the drug seemed suddenly very important. I will not take the poison again. Below is everything you need to know about alendronic acid, commonly prescribed by doctors to treat bone conditions. Take the medicine on an empty stomach. I took Alendronic Acid for 6 months and stopped 5 months ago. Many thanks for all your comments re Alendronic Acid, these have been most helpful in my decision to take this drug. In April 2010 I went back to my gym routine, and within a few weeks the second jerking episode occurred. The NHS say. Other side effects include: arthralgia, myalgia, and ostealgia. I only took one pill but think I will stop. This was long ago and it was a new drug but the GMC told my GP that yes there was a slight risk of an allergic reaction to it. Terms|Privacy, Research Forum for Enduring Sexual Dysfunction, https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA, https://www.druglawsuitsource.com/canada-fosamax-lawsuits-settled/. I have had to keep off coffee, fruit and anything acidic for months, I even tried gaviscon which made me feel sick and had a bloated stomach for 2 hours. Alendronic acid | C4H13NO7P2 | CID 2088 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . Alendronate is used to prevent and treat osteoporosis. Its bad enough living with PBC and all that entails for the rest of my life, but to go through what all of you good people have gone through NO WAY DANNO! In a typical nanoconstruct, alendronic acid is conjugated with hydrophilic head moiety of phospholipid that has an ability to self-assemble with hydrophobic polymeric core through its hydrophobic long carbon-chain. Anyway, I started to take them three weeks ago and I seem to have been fortunate in that I have had very few side effects but, after reading all these reviews, Im not sure I will carry on as Im fit and healthy with no pain. Because of how I tend to react and my blood test results, I thought I would research the new meds first and Im now very pleased that I did. Im also having episodes of increased heart rate on a regular basis just from walking a short distance. Instead of the exercising I need and want to be doing, my muscles are weakening, my joints ache, my tendons burn and my bones are probably crumbling away. I suggested, because of the Seroxat link, that I might be sent to a Seroxat specialist. blurred vision, painful or red eyes - these can be signs of swelling of the eye. If I apply pressure to the back of my neck, my neck pain still hurts really bad, but I can move my neck. In 2002 I discovered via the internet that I wasnt desperately ill with an anxiety disorder that only Seroxat could fix. Alendronic acid, which is a generic drug that is also supplied under the brand name Fosamax Once Weekly (Organon Pharma), is licensed for the treatment of postmenopausal osteoporosis, according to the supply notification. Im going to stop taking Alendronic acid. Their non-medical use was to soften water in irrigation systems used in orange groves. I am now using a Naturopathic Bone Protocol supplentation for building bones. Bisphosphonates are a class of osteoporosis drugs such as Boniva (ibandronate), Fosamax (alendronate), Actonel (risedronate) and Reclast (zoledronic acid). I felt pressurised to take it saying that I would suffer as I get older if I didnt take it but I am now wondering if it really does any good. This study is a randomized, double-blind, placebo-controlled 2-year study. Not feel normal anymore, weak dizzy loosing balance and sight too which could also be caused by oprazole to protect stomach. Alendronic acid is a type of medicine called a bisphosphonate. There are over 200 million people worldwide who have osteoporosis. Want to take back controle before I find myself surrendering myself to more drugs. oscar the grouch eyebrows. To summarise, my probs appear to be muscular. I went back to my GP to inform him that I couldnt take them and he readily gave me another prescription for Risedronate 35mg one a week which I am now frightened to take because the possible side effects listed are exactly the same as the AA. thanks for this site. I felt so incredibly ill the next day. Took my 1st AA 2 days ago, since then Ive had constant stomachache, feel exhausted, and tired, and shivering. Drinking alcohol for about two standards per day may increase your risk of bone fractures. I have even had to report my concern and disappointment and lack of care by both my GP and Dentist. pope francis indigenous peoples. Make sure the spinach is cooked to get rid of the oxylates which inhibit calcium absorbtion; so cook your spinach. I am aldo taking Calcio with vitamin-D Blood test in November showed a underactive thyriod and am taking Levothyronine 25mg. They began to itch the next day, ( I took my 5th dose of medication) and they were slightly better but I called my doctor and got in To the office Friday. I had settled on a very low dose of Seroxat, enough to keep withdrawal at bay but not enough to have a therapeutic effect, because I didnt need one. My 76yr old mom has taken 7 AA tablets and it has cause her hip, leg and groin pain that has become quite severe. It usually takes 6-12 months of taking alendronic acid to support your bones. By this time my body was still, so I went home feeling scared and utterly distraught. Are there any better options to AA which people have found?? Thanks. I have had 7 weeks off work with a fractured wrist and another week off with feeling poorly due to AA (with no pay as Im a self employed carer) and need to feel fully fit before returning to work. Withdrawal was so extreme that the longest I ever lasted off the drug was seven weeks, the worst of my life. Stopping and seeing if the symptoms resolve for most drugs is the best way to prove a link some problems with some drugs may take time more time than you expect but will resolve but some may also be permanent. She has stopped the tablets. Alendronate works similarly to other bisphosphonate drugs like risedronate, ibandronate, zoledronic acid, pamidronate, and etidronate. Having read all the above I am going to see my doctor again about this drug. Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. My body awareness tells me otherwise. re the first strange vivid dreams has been my nearest experience. I was told that it was very uncommon what happened to me, and it was my choice to take it again next week or not. I would say) I was suddenly aware of my mouth being transformed into a state where I was unable to move my lips and then my jaw at all. This was a total surprise to me. Gave up Alendronic Acid recently after a random chat with a friend! I wonder if it might be something that could help you Ive attached the link to the video below. I hd bone density DXA scan scan in 2010 and was told i had Unfortunately, Im pretty intolerant to most drugs, other than HRT, which I took for 5 years without any side effects and made me feel fantasticuntil my GP refused to prescribe them once I reached 50. Hi, my story is very similar but I only found out today that Alendronic Acid has caused my dental problems. I was thinking maybe I was dehydrated, so I drank a few bottles of purified water. Im very concerned and unsure what to do? I am 73, have Secondary Progressive Multiple Sclerosis and I was prescribed Aldronic Acid 1 a week since breaking my femur in 2015. Like just for a moment I couldnt remember where I kept my masking tape. Have been on it a yr. Was ok i think, but disabled badly with fatigue anyway, so hard to know. The next day I felt very ill. Warnings From day one I didnt believe that my body needed them but was told that When your taking steroids the additional meds are also needed & I was told this by more than one GP!!! My lower face is completely swollen on the left side. I have gone downhill and increased weight. Wait for at least 30 minutes after taking the drug. I was told i had Oesteoporosis of the spine with high risk of a fracture. I also broke my hip, which made it even more difficult to do anything at all. If I apply pressure to my temples, my headache lessens. However, it usually takes 6-12 months of ongoing medication to get its full benefit. On research I found there has been class law suits against the manufacturer of this drug in Canada. H411 (50%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment . Im sure they will sound familiar. You can only stop taking alendronic acid when your doctor says so. She was told her bones were fine but should continue on Alendronic Acid. It was the most frightening and totally incomprehensible thing to have no control over my limbs at all but as I sit and write this, I realise it has become totally familiar. When I initially had a bone scan they said Id have another one after three years, Ive never had another one. This way, youll prevent any irritation in your throat or esophagus. As I was searching through my kitchen drawers, it came to me. Eventually I asked to see a movement disorder specialist, as by this time I was convinced I must have some dreadful neurological problem. I would be grateful for any help or advice I have had OA in my lumber Thorasic and Cervical regions of my spine and also in both of my hips and was given a Bone density scan which showed the OA has progressed to Osteopena for this the consultant prescribed Alendronic Acid tablets 70mg which I take once a week from 30/03 /13 . Now on Alendronic 70 weekly. My appointment is on the 23rd August 1017 and I am now very concerned. Sight has deteriorated (but attend Moorfields for regular check ups. I also have arthritis in my thumbs. Not far into the walk (about 20 mins. Please check with your doctor before stopping taking alendronic acid and switching to alternative treatments. Thanks so much & best of luckKatie (New York), I had a fall downstairs nearly 2 years ago and broke my back, Ive been on adcal 3 for years do my doctor put me on alendronic acid, since then my health has been awful, Im 66, it takes me to get out of bed in the morning I can hardly walk at times,my teeth are crumbling asked dentist was it because of the tablets he said no but Im sure it is,Ive up get a root extraction on Thursday as my tooth crumbled and left the root of the tooth,he said he is concerned about me being on the alendronic acid and if he cant get the root out I will be sent to hospital,thats me finished with these tablets they have ruined my life. This pain was far worse than the pain I experience withOsteoporosis! This settled after a few days I have osteopenia aged 58 and my sister has osteoporosis aged 65, she was prescribed Alendronic Acid with similar side effects. Its been a nightmare for four weeks weeks. No tablet is worth taking if no quality of life. Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Hi, Ive just discovered this site. A novel process for the preparation of alendronic acid is disclosed. Where do you live Jane hope you dont mind me asking. My worry at the moment is that I need a new crown in my teeth and do not know if this permitted and if I go ahead will it affect the health of my gums. After reading about it I returned the box of tabs unused. Thus, it helps increase bone density, reduce the risk of bone fractures, and treat osteoporosis. I was determined that my own actions would build my bones so I only had to take the drug for a short time. reduce the risk of fractures in people with osteoporosis. I would really welcome views on whether a reading of -4.5 is too high to be able to treat with exercise, diet and supplements. This full head pain is extremely bad. I was put on alendronic acid 70mg and in 2013 Background: The objective of the study was to evaluate the effects of alendronic acid once weekly relative to risedronic acid once weekly on bone mineral density (BMD), markers of bone turnover and tolerability in the treatment of osteoporosis in postmenopausal women. Bottom Line. Had another car ride, but then it flared up again, sometimes I limped all morning. http://www.ehealthme.com/cs/osteoporosis/drug+intolerance, http://www.ehealthme.com/cs/osteopenia/drug+intolerance, http://www.ehealthme.com/ds/fosamax/drug+intolerance. I was able to see a neurologist fairly quickly, and he concurred with my thoughts that it was probably Seroxat clashing with the anti-sickness tablets (metaclopromide) I had taken in September, and therefore a one-off event. HI all I fractured my wrist in October had a dxa scan and was told I had osteoporosis. It is a condition when you have fragile bones, making you prone to bone fractures or breaks from daily activities such as walking or standing. Has anyone has this done ? Summary Commonly reported side effects of alendronate include: decreased serum calcium and decreased serum phosphate. A blood test followed and the inflammation was evident in the test, but I did not test positive for RA which I was worried about. This makes them at high risk of developing osteopenia or osteoporosis. 6.3 Shelf life. Ive only taken one tablet going to speak to Dr tomorrow. Stopped now. I left the surgery with a diagnosis of being on the edge of a clinical depression and a prescription for Seroxat. They did prescribe adcal calcium/vit d and felt so ill which I thought was these drugs causing it but it wasnt it is intolerance to calcium which I was told when I had my bone scan is quite common. Am I the only one the suffer from these bad side effects after taking it for the first time. Pharmaceutical drugs are just about making money and not curing people. where do I go from here, the last thing I want is dentures !! . They can help to: prevent bone loss caused by hormone therapy and other cancer treatments. What an awful time you are having my sympathy goes out to you. I would like to take an alternative to alendronic acid wuth some exercises for the spine. I also have had a bone scan pre drugs so it would be interesting to find out when I can have another scan to see whether there is an improvement or at least no further loss apart from normal degeneration of bone. I had also gone hypothyroid. I have now been off Alendronic acid for two weeks or so, and at the moment im not noticing very much improvement. Continue reading for a comprehensive list of adverse effects. Thank you. Sister told the doc she intends taking Boron. There is nothing I can do to stop the shoulder pain, and lower jaw pain, or the chills I get. Ive not been offered another dexascan in four years but if this swelling goes down my GP can decide what he wants to do about treatment, if any. Severe side effects include the following: In rare cases, alendronic acid may cause a severe allergic reaction (anaphylaxis). Bisphosphonates are often the first treatment you'll be offered if you have weaker bones. Same here. Do not take this drug if you have mild to severe kidney problems. Its essential to take calcium supplements and vitamin D3 at least 2-4 hours before your first dose of alendronic acid. I will never take drugs like yours again. Doctor said it was a preemptive measure as my left hip was compromised! Looking back over the past four years of this journey, I realised that whenever I took any other tablets my symptoms worsened dramatically. I was still a little sore, but improving. Even before Fosamax was introduced in 1995 as a superior osteoporosis treatment, jaw osteonecrosis has been linked to the bisphosphonate drug family. If I took slow shallow breaths the pain was bearable. I am otherwise healthy and have never taken any meds in my life. She doesnt have osteoporosis. Felicity It hurts to walk on my feet. I urge you to Look into his work for yourselves. Overdosing may lead to an upset stomach, heartburn, and ulcers. My rheumatologist prescribed AS but I dalayed taking as I had lots of dental work to be done. Federal drug regulators and researchers say that Fosamax, a drug thats supposed to help with bone growth, is linked to this rare dental disease thats also called Dead Jaw Syndrome. Ive been prescribed alendronic acid now as although doing very well year later, my new doctor is concerned about my bone and muscle condition. Stopping this medication means maintaining your bone health and density through lifestyle and diet. Menopause in women or low testosterone levels in men, Poor nutrition such as low-intake of calcium and vitamin D, Crohns disease, celiac disease, and other inflammatory bowel conditions that affect your body in absorbing nutrients, Calcium supplements, magnesium, iron, and zinc multivitamins, Cancer medicines such as bevacizumab or thalidomide and if youre undergoing chemotherapy. Im considering ringing the hospital myself to see if I can have one done. treat cancer that has spread to the bone ( secondary bone cancer or bone metastases). Thank you for your comment. muscles ache, no energy, depression. Alendronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. Dont use it. The hygienist cleaned my teeth a few weeks ago. Avoid taking it if you have esophageal or throat conditions. I was such an idiot for believing in this drug! But, theres not enough evidence on this claim. What are we paying the doctors for? I slept restless, my shoulders began to hurt. Itching in my left shoulder/arm, have gained weight and my mood has changed. Alendronic Acid 70 mg tablets is a tablet containing the active substance alendronic acid (commonly called alendronate) and belongs to a group of non-hormonal medicines called bisphosphonates. But no issue with my teeth. It's harmful if you suddenly stop taking it without a proper assessment from your healthcare provider. Editorial Note: We want any accounts of adverse or interesting events on drugs or new uses for drugs from people on them or doctors, pharmacists or others trying to manage the effects of drugs. It's harmful if you suddenly stop taking it without a proper assessment from your healthcare provider. Results are insufficient to support the use of alendronic acid in paediatric patients with osteogenesis imperfect. I really think the doctors for whatever reason are unable to tell people to eat right and exercise i.e. I have been taking this drug since 2006 only to be told today at a meds review that it should only be used for a limited time. Many thanks, Diagnosed with myasthenia gravis in January and prescribed boat load of tablets.